Among other protein domains, we focused on BIR-containing proteins (putative inhibitors of apoptosis), because apoptotic responses are reported as one of the main bivalve countermeasures to infections due to the μVar variant (Segarra et al., 2014b; He et al., 2015; Martenot et al., 2017) and BIR was found in several dsDNA and ssRNA viruses of invertebrates. The gene discussed is KCNJ11; the disease is infection.