IFN-γ+ cells were increased in both groups, especially in the ones with HT + NEAD (19 versus 29.9%; P = 0.0082), while a higher number of IL-4+ cells was reported in 9.1% of patients with isolated HT and in 71% with HT + NEAD (P < 0.0001; relative risk = 3.18). Here, IL4 is linked to hematocrit.