VEGFA and neoplasm: These cells can enhance tumor angiogenesis, immunosuppression, tumor cell invasion and metastasis via the production of different cytokines and chemokines such as VEGF-A, CCL17/CCL22, and EGF (Columba-Cabezas et al., 2002; Goswami et al., 2005; Murdoch et al., 2008).