NRIP1 has been suggested as a potential candidate gene in autism, on the basis of in silico analysis of chromosomal regions involved in an unbalanced rearrangement del(21)(q11.2q21.2), identified in an ASD patient from a cohort of 126 ASD patients through high-resolution comparative genome hybridization (Iurov et al., 2010). The gene discussed is NRIP1; the disease is autism.