In addition, a high percentage of NK cells of the tumorigenic phenotype CD3−CD49b+ and phenotypes involved in tumor elimination, for example, CD8+CD11c+CD83+CD86+iNOS+MHC-II and DC-Lcd11b+ macrophages, was observed, along with high levels of IFN-γ and IL-12 Th1 cytokines and the percentages of CD8+ cells. The gene discussed is CD8A; the disease is neoplasm.