It has been reported that miR‐200c inhibits MMP‐3 expression, which in turn abolishes ovarian cancer metastasis (Sun et al., 2014), downregulates E‐cadherin, and affects the EMT in human renal cell carcinoma (Wang et al., 2013), as well as targeting the 3′‐UTR region of jnk2 mRNA to inhibit the metastasis of colorectal cancer (Sui et al., 2014). This evidence concerns the gene MMP3 and renal cell carcinoma.