FN1 and neoplasm: Other authors have analyzed imaging of the ED-B domain of fibronectin using PET isotopes, such as 76Br and 124I, which labeled always to antibody fragments; the potential use of 124I-L19-SIP appears very interesting, not only for immuno-PET imaging of tumor angiogenesis, but also as a guide for 131I-L19-SIP radio-immunotherapy [66,67].