Secondly, to investigate whether TDT could targeted delivery anticancer drugs to CD123 + tumor cells and avoid damaging CD123− cells, CD123+ cell line Molm-13 and TF-1, CD123− cell line RCH-ACV and EL4 were treated either with TDT, ZW25-OCDLS, ZW25 or free Dox. The gene discussed is IL3RA; the disease is neoplasm.