ERBB2 and breast cancer: In a recent study, Manson et al. reported that dietary flaxseed presented minimal tumour-reducing outcome did not interfere with trastuzumab action (a recombinant humanized monoclonal antibody used as the first-line therapy in HER2-overexpression breast cancer) but enhanced survival in athymic mice with established HER2-overexpressing human breast tumours [288].