AKT1 and breast cancer: Research studies referred to different molecular mechanisms underlying the antitumour activity of curcumin in breast cancer cells, such as modulating the NF-ƙB signalling pathway [296, 297, 301–303], decreasing HER2 oncoprotein expression, the phosphorylation of Akt, MAPK, the expression of NF-ƙB in both BT-474 and SK-BR-3-HR cell (i.e., a herceptin resistant strain from SK-BR-3) [304], and the induced apoptosis by inhibiting fatty acid synthase [305].