WT1 and chronic kidney disease: However, our data may also suggest that because the histology of WT is similar to that of fetal kidneys and the WT1 transcription factor expression may be required for kidney development and normal organ function and considering that WT cells may share chromatin profiles intimately connected to kidney organogenesis, a link between the use of iPSs and kidney regeneration could be possible and therefore a promising treatment for CKD [42, 50].