Tau plasma levels in all SCD participants with available CSF did not correlate with CSF levels of Aβ42 (β = 0; 95% CI −0.001 to 0.001, p = 0.663), tau (β = 0.001; 95% CI −0.004 to 0.001, p = 0.298), and p-tau181 (β = 0.011; 95% CI −0.027 to 0.005, p = 0.171) after controlling for age, gender, and education. The gene discussed is MAPT; the disease is Schnyder corneal dystrophy.