WNK2 and central nervous system cancer: Suppression of galectin-1 can sensitize lung cancer cells to cisplatin by up-regulating p38, mitogen-activated protein kinase, the extracellular signal-regulated kinase (ERK), and cyclooxygenase-2 [11,12] and down-regulating galectin-1 expression may promote sensitivity toward the proapoptotic and proautophagic drugs in glioma [27].