Poly(I:C), as expected, up-regulated genes associated with inflammation, innate immunity and viral responses including CXCL11, CCL5 (chemokine (C–C motif) ligand) 5 and CXCL10, interferon-induced protein 44 like (IFI44L) in ASMCs from both healthy non-cough and chronic cough volunteers. The gene discussed is CCL5; the disease is Cough.