NPPB and acute kidney injury: As for parameters of inflammation and organ function, the following were all significantly different in the AKI group compared with in the non-AKI group: CRP, BUN, serum creatinine, cystatin C, BNP, albumin, hemoglobin, lactate, the proportion of patients with septic shock, nonrenal SOFA score, and number of overt DIC cases.