ICAM1 and acute kidney injury: In two other studies, researchers found that levels of E-selectin significantly increased in cases of AKI in sepsis, but they measured only the levels of intracellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1), and E-selectin as markers of endothelial injury and did not measure coagulopathy [12, 13].