As for parameters of inflammation and organ function, the following were all significantly different in the AKI group compared with in the non-AKI group: CRP, BUN, serum creatinine, cystatin C, BNP, albumin, hemoglobin, lactate, the proportion of patients with septic shock, nonrenal SOFA score, and number of overt DIC cases. This evidence concerns the gene CST3 and acute kidney injury.