A striking observation was that infected mice pre-treated with L. plantarum (Lp/Lepto), which we had previously determined to have less kidney damage (Figs 2 and 3), had a marked increased in NIMP-R14+ neutrophils and F4/80+ macrophages (at least 2 fold higher) as compared to infected PBS-treated controls (PBS/Lepto), (Fig 8B and 8C). This evidence concerns the gene RTN4IP1 and urogenital neoplasm.