Moreover, the regulation of SP1 by BBR was also found in other studies; death‐domain‐associated protein (DAXX) regulated many cellular signalling pathways for cell growth and apoptosis, and through disrupting the association of SP1 binding to the DAXX gene promoter, BBR inhibited the DAXX promoter activity, thereby inducing human neuroblastoma cell apoptosis45. Here, SP1 is linked to neuroblastoma.