Study showed that interleukin 6 (IL‐6) increased the expression of DNMT1 in lung cancer cells, and that knockdown of DNMT1 reversed IL‐6‐mediated hypermethylation of cell cycle regulatory genes and enhancement of lung cancer stem‐like properties, implying that IL‐6‐mediated pathway increased DNMT1 expression and enhanced lung cancer stem cell (CSC) proliferation 26. Here, DNMT1 is linked to lung carcinoma.