The mean age was 14.2 ± 2.0 years, duration of diabetes 8.3 ± 3.2 years, HbA1c 7.7 ± 0.6% (60.0 ± 6.6 mmol/mol), duration of pump therapy 7.4 ± 3.2 years and the total daily insulin dose 0.8 ± 0.2 U/kg. The gene discussed is INS; the disease is diabetes mellitus.