IL-18 provocation increased percentage of IL-18BP+ mast cells in both inflamed (Figure 4(g)) and uninflamed skin areas (Figure 4(e)) of mouse eczema skin (Figure 4(h)) by 38.2% and 26.2% in comparison with that in healthy skin of mice (Figure 4(c)). This evidence concerns the gene IL18BP and Eczematoid dermatitis.