Although topical ocular application of drug using biodegradable in situ gelling carriers has been shown to achieve longer therapeutic action, the EGCG-containing GN cannot completely relieve dry eye symptoms, as indicated by a relatively high rose bengal staining score and comparable goblet cell number and ocular surface mucin expression to those of rabbits immediately following BAC treatment. This evidence concerns the gene MUC5AC and minimally invasive lung adenocarcinoma.