ADAMTS13 and thrombophilia: ADAMTS-13 activity had a significant independent effect on α (estimate = −0.50 ± 0.17, p = 0.006) and K (estimate = 0.44 ± 0.17, p < 0.001) with a fall in ADAMTS-13 activity being associated with increased speed of clot formation, in agreement with the hypercoagulability and fall in ADAMTS-13 activity seen at 12 h.