VEGFA and hepatocellular carcinoma: Kong et al. (2007) studied a total of 19 allele VEGF gene polymorphisms in HCC, these findings suggest that the -2578 to -1498 region of the VEGF gene showed strong linkage disequilibrium (rs699947; rs1005230; rs12210204; rs833061), and VEGF polymorphisms located at promoter region were associated with HCC progression [9].