Thus, the QTL on Chr7 (peak 37 cM, CI = 23–48 cM), DBA allele which is protective for B6 root atherosclerosis, co-localizes with the female-specific Ath31 locus revealed in F2 populations of B6-apoE and Apoe-null on C3H/HeJ (C3H) background (C3H-apoE) [27]. Here, APOE is linked to atherosclerosis.