MBL2 and autosomal dominant cerebellar ataxia: Oliveira et al. (2009), in an analysis of the relationship between the genotypes of MBL2 exon 1 in children with SCA identified an association between the AO/OO genotypes and VOC (p = 0.039; OR = 3.01; 95%CI = 1.05-9.11). In addition, this population showed an association between polymorphism in the promoter region −221 and exon 1 of MBL2 in relation to VOC (p = 0.0188; OR = 3.15; 95%CI = 1.19-8.50) (Mendonça et al., 2010).