CHAC2 and colorectal cancer: And the CHAC2 expression (HR:0.380; 95% CI: 0.202–0.711; P=0.003) and histopathological grading (HR:1.428; 95% CI: 1.042–1.957; P=0.027) were proved to be independent prognostic factors for survival in colorectal cancer (Supplementary Table S7).