17 Expectedly, in vivo, Treg responses are necessary for complete restoration of insulin sensitivity and dyslipidemia.16, 17 Adropin is involved in the mechanism of increased adiposity, insulin resistance, and glucose and lipid metabolism.18 More interestingly, we found that almost all patients with pancreatic steatosis were diagnosed with diabetes; in addition, Enho mutations were found in a three-generation family of Chinese origin with the common feature of T2DM attacks and FP. Here, ENHO is linked to metabolic syndrome.