In particular, 74.4% of G1 patients did not express PD-L1-positive infiltrating cells, suggesting that G1 patients may have different tumor immune interference mechanisms: the 25.6% of positive G1 patients showed a weak PD-L1 signal in 5 (50%, 13% of the total) and moderate in the other 5 (50%, 13% of the total) (Table 3). This evidence concerns the gene CD274 and neoplasm.