miR-323a-3p belonging to the DLK1-DIO3 genomic imprinted miRNA cluster is located at chromosomal region 14q32.31, and functions as a tumor suppressor in several different types of human tumors such as prostate cancer and pancreatic ductal adenocarcinoma.25, 26, 27 However, its specific role in BCa has not been elucidated so far. Here, DIO3 is linked to prostate cancer.