Furthermore, she tested positive for islet-specific (GAD, IA-2 and zinc transporter 8 [ZnT8]) as well as thyroid-specific (thyroid peroxidase and thyrotropin receptor) autoantibodies, and ketone bodies were found in urine, prompting the diagnosis of Graves’ disease and type 1 diabetes following the criteria defined by the ADA. The gene discussed is TSHR; the disease is Graves disease.