Another diagnosis study about HULC was from Li et al. Of eight possible lncRNA candidates (UCA1, TUG1, CCAT1, MEG3, Linc00152, HULC, MALAT1, and GAS5), circulating HULC and Linc00152 were significantly upregulated in plasma samples from HCC patients during training and validation sets using qRT-PCR, with areas under the ROC curves of 0.78 and 0.85, respectively. This evidence concerns the gene MALAT1 and hepatocellular carcinoma.