With this interdisciplinary approach, the genotype-to-phenotype relationship was better understood for critical cancer-related genes, such as BRAF (B-rapidly accelerated fibrosarcoma), KRAS (K-RAS oncogene), P53 (P53 transcription factor), and EGFR (epidermal growth factor receptor), with relevance in cancer therapy studies [85]. This evidence concerns the gene KRAS and cancer.