ARHGAP31 (CdGAP) mRNA levels showed an overall negative correlation with total levels of E-cadherin protein in TCGA datasets, which was significant in stomach adenocarcinomas, ovarian cancer, colorectal adenocarcinomas, bladder and breast carcinomas (Fig. 1I; see methods). This evidence concerns the gene ARHGAP31 and colorectal adenocarcinoma.