TCF4 and Fuchs endothelial corneal dystrophy: However, our differential gene expression analysis data (unpublished) and reported studies [28, 43] have shown that expression levels of TCF4 mRNA in the corneal endothelium between FECD cases and controls and between carriers of risk and non-risk alleles of SNP rs613872 are similar indicating that transcription inhibition likely is not involved in the pathogenesis of FECD.