ADCYAP1R1 and cyclic hematopoiesis: We selected the top three associations from Bacchelli et al.; rs1006417, an intergenic variant on chromosome 14q21; rs12668955 in adenylate cyclase activating polypeptide 1 receptor type 1 (ADCYAP1R1) and one rare mutation, rs147564881, in the membrane metallo-endopeptidase gene (MME), and performed a replication study on a well characterized and large Swedish CH case-control population.