MALT lymphomas are B-cell derived with CD20 expression and frequently contain numerous admixed CD3+-reactive T cells.18,19 Unlike chronic lymphocytic leukemia/small lymphocytic lymphoma and mantle cell lymphoma, the lymphomas of MALT origin usually lack CD5 and are without bcl-2 gene rearrangements.20 MALT lymphomas differ from follicular lymphomas in that they are negative for CD10 and do not exhibit bcl-2 rearrangements.20 The immunophenotypic results of the current biopsy samples along with the characteristic histologic features led to the confirmation of MALT lymphoma. The gene discussed is BCL2; the disease is mantle cell lymphoma.