The Foxp3+/CD8+ ratio was significantly higher in LNs with metastases of adenocarcinoma when compared to the negative LNs (median value, (p25–p75): A = 0.40 (0.30–0.50) versus B = 0.25 (0.25–0.33), p < 0.05); see Figure 3. The gene discussed is CD8A; the disease is adenocarcinoma.