Figure 4(a) lists the top 10 targets that are most frequently interacting with DIM drugs. It could be seen that the cytochrome P450s family dominated, indicating that the metabolism is playing a crucial role in the mechanism of DIM. It was reported that statin drugs that usually cause myopathy through statin metabolism via the CYP system [18]. Then, we mapped the 10 protein targets into STRING 9.3 PPI network to investigate whether they are interacted with each other (Figure 4(b)). Here, PPIG is linked to myopathy.