Results showed that IL-23, EBI-3 (IL-27 beta subunit), IL-12p40, IL-12p35, IFN-γ, IL-6, and IL-10 mRNA expression were all increased both in the liver and in the spleen during PbNK65 hrfΔ infection as compared to WT infection (Supplementary Fig. 2A,B). This evidence concerns the gene EBI3 and infection.