Multiple key genes in Wnt/FZD and Wnt-associated endothelial mesenchymal transition (EMT) signaling pathways were differentially modulated by the presence of FZD4-miR-SNP in NSCLC cells as demonstrated by a quantitative NanoString Wnt/EMT-pathway specific gene expression analysis. Here, FZD4 is linked to non-small cell lung carcinoma.