FCGR3A and HIV-1 infection: The possibility that our CD4-based BiKEs can bind all HIV-1 isolates, their small size and fully human origin, combined with their high-affinity and specific, activating interactions with CD16A resulting in lysis of HIV-1 infected cells suggest that they are promising candidate therapeutics and worth of further evaluation in animal models and potentially in humans for therapy of HIV-1 infections with the final goal of its eradication.