BRCA1 and breast neoplasm: We created a nonBRCA tumor set (n = 764 breast, n = 215 ovary) from the remaining TCGA tumors excluding tumors with somatic mutations in, homozygous copy loss of, or transcriptional repression of BRCA1 and/or BRCA2, and any breast tumors from patients who had received neoadjuvant chemotherapy.