XIST and central nervous system cancer: Data were displayed as described; the TMZ concentration to reduce cell viability to 50% (lC50) for U251/TMZ and LN229/TMZ was significantly reduced by XIST knockdown, whereas increased by miR-29c, indicating that XIST knockdown reduced the chemoresistance of glioma cell to TMZ whereas miR-29c inhibition played an opposite role.