In addition, several studies documented elevated levels of MCP-1 in the vitreous humor of patients with retinopathy [59, 60], and in animal models, MCP-1 was shown to be involved in the induction of the retinal neovascularization possibly by modulating or attracting macrophages/microglia during the ischemic phase of retinopathy [61, 62]. The gene discussed is CCL2; the disease is retinal disorder.