Additionally, analysis of a dataset of gene expression in GSCs compared with normal glioma cell lines (GSE23806) revealed that LAMTOR3 expression was significantly higher in glioma cells with stemness (i.e., both glioma cells established by neurosphere culture and GSCs) in parallel with high FABP7 and SOX2 expression than in normal glioma cell lines (Additional file 5: Fig. S4E). Here, SOX2 is linked to central nervous system cancer.