TGFB1 and sarcoma: Studies in the past 20 years have shown that the EMT is associated with various cancer-related processes, including metastasis and induction of tumor progression/metastasis in several types of sarcoma[5].Various transcription factors or secreted components, including fibroblast growth factor, hepatocyte growth factor, transforming growth factor-β1 (TGF-β1), and β-catenin[6]can contribute to or are required for the EMT/MET.