NFKB1 and neoplasm: An additional mechanism of NF-κB inhibition that is being viewed with increasing interest is mediated by the tumour suppressor, WW domain-containing oxidoreductase (WWOX), which is frequently inactivated by gene mutation, deletion or chromosomal translocation in multiple types of haematological and solid cancer [94,95,96,97,98,99,100,101,102].