Congruently, certain NF-κB-dependent multiple myeloma cell lines express low levels of GADD45β and are completely refractory to DTP3-induced killing [200], confirming the existence of GADD45β-independent mechanisms for NF-κB-dependent survival in certain subtypes of multiple myeloma, and such mechanisms are certain to also exist in other types of malignancy. This evidence concerns the gene GADD45B and plasma cell myeloma.