Congruently, certain NF-κB-dependent multiple myeloma cell lines express low levels of GADD45β and are completely refractory to DTP3-induced killing [200], confirming the existence of GADD45β-independent mechanisms for NF-κB-dependent survival in certain subtypes of multiple myeloma, and such mechanisms are certain to also exist in other types of malignancy. Here, NFKB1 is linked to plasma cell myeloma.