CXCL8 and chronic myelogenous leukemia, BCR-ABL1 positive: The analysis on a human CML cell line, LAMA84, revealed that CML cell-derived exosomes stimulated bone marrow stromal cells to produce CXCL8 that, in turn, was able to enhance the capacity of CML cells to migrate and to adhere to stromal cells, and to promote CML cell proliferation both in vitro and in vivo [96].