NPPB and Patent ductus arteriosus: Many biochemical markers have been correlated with PDA such as B-type Natriuretic Peptide (BNP), the segment of the amino terminal B-type Natriuretic Peptide (NT-proBNP), and the cardiac Troponin T (cTnT), whose levels increase in case of hsPDA with right to left shunt, and could help in disease staging and management [5, 12].