F3 and type 2 diabetes mellitus: The overall expression pattern of JAG1 is similar to that of the gene Coagulation Factor III (F3) (correlation >  0.7), genetic polymorphisms of which have been shown to be associated with T2D in different ethnicity groups (Palmer et al., 2012; Yamada et al., 2006; Yamaguchi et al., 2007) and the expression of which is significantly higher in monocytes and neutrophils of diabetes and prediabetic subjects (Ichikawa et al., 1998).