The median serum FGF-23 level in HD patients was significantly higher than that in the RTRs (460.7 [269.2–2326.0] vs. 297.3 [200.0–1494.0] pg/mL; p<0.01); both of these groups, however, had significantly (p<0.05) higher FGF-23 levels compared to the control group (236.4 [86.9–422.50] pg/mL; p<0.01 vs. HD, p<0.01 vs. RTR)—FGF-23 level: HD patients>RTRs>controls (Table 2). The gene discussed is FGF23; the disease is Huntington disease.