CAV1 and neoplasm: In the nonepithelial compartment, Cav-1 was more frequently expressed in fibroblast-like cells, endothelial cells, and smooth muscle within the stroma surrounding tumor nests more than tumor cell, and loss of stromal Cav-1 expression was found in 57 of 141 cases (40.4%), which is consistent with the previous studies [10, 18].